涂层
聚吡咯
材料科学
脚手架
沉积(地质)
电化学
组织工程
化学工程
骨生长
表面改性
模拟体液
复合材料
生物医学工程
聚合物
化学
扫描电子显微镜
生物
沉积物
内科学
工程类
物理化学
古生物学
医学
聚合
电极
作者
Ting‐Ting Li,Shiqi Wang,Jiaxin Li,Ying Zhang,Xing Liu,Liyan Liu,Hao‐Kai Peng,Haitao Ren,Lei Ling,Jia‐Horng Lin,Ching‐Wen Lou
标识
DOI:10.1080/09205063.2023.2265134
摘要
When impaired bones are grafted with bone scaffolds, the behaviors of osteoblast are dependent on the implant materials and surface morphology. To this end, we modulated the surface morphology of scaffolds that promote cell growth. In this study, ice-template and spraying method methods are employed to coat different proportions of PDA and PPy over the PLA/PVA weaving scaffolds, after which HA is Coated over via the electrochemical deposition, forming weaving scaffolds with electrically conductive PDA/PPy/HA coating. The test results indicate that with a PPy/PDA concentration ratio is 30, the PPy particles are more uniformly distributed on the fiber surface. The scaffolds are wrapped in a HA coating layer with a high purity, and calcium and phosphorus elements are evenly dispersed with a Ca/P ratio being 1.69. Owing to the synergistic effect between PDA and PPy coating, the scaffolds demonstrate excellent electrochemical stability and electrochemical activity. The biological activity of the scaffold increased to 274.66% under electrical stimulation. The new thinking proposed by this study extends the worth of applying textile structure to the medical field, the application of which highly increases the prospect of bone tissue engineering.
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