衰老
慢性伤口
伤口愈合
细胞衰老
医学
细胞
生物
外科
内科学
遗传学
表型
基因
出处
期刊:PubMed
[National Institutes of Health]
日期:2023-08-20
卷期号:39 (8): 795-800
标识
DOI:10.3760/cma.j.cn501225-20220928-00424
摘要
Chronic wounds bring huge pressure and difficulties to patients, their families, and society due to their long-term refractory characteristics and serious poor prognosis. Recently, more and more evidences have proven that cell senescence exists in chronic wounds and affects wound healing. This article reviews the characteristics of cell senescence in chronic wounds, discusses the relationship between cell senescence and chronic wound healing, and summarizes current series of anti-senescence strategies to bring out the possibility of treating chronic wounds with cell senescence as a potential target.
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