Nano-Biosensors and Nano-Biochips in Moving Nano-Particle Molecules Through Dielectric Enhancement Through Vertical Nano-gap Architectures

Note: The dynamic process of sorting and precise positioning of nano particle biomass in pre-defined microstructures is very important, however, this is a major obstacle to the realization of surface-sensitive nanobiosensors and practical nano bio chips.A scalable, widespread and non-destructive trapping method based on dielectric forces is much needed for nanoparticle collection and nanobiosensing tools. Here, we present a vertical nanogap architecture with an electrode-insulator-electrode stack structure. Facilitate the generation of strong dielectric forces at low voltages, for precise capture and manipulation of nanoparticles and molecular assemblies, including lipid vesicles and amyloid-beta fibrillar proteins/oligomers. Our vertical nanoplastic platform allows low-voltage nanoparticles recorded in optical dimensional designs, providing new opportunities for the fabrication of advanced surface-sensitive sensors.