Time-Restricted Feeding Enhances Early Atherosclerosis in Hypercholesterolemic Mice

HomeCirculationVol. 147, No. 9Time-Restricted Feeding Enhances Early Atherosclerosis in Hypercholesterolemic Mice No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextTime-Restricted Feeding Enhances Early Atherosclerosis in Hypercholesterolemic Mice Chang Pan, MD, Beatriz Herrero-Fernandez, MSc, Celia Borja Almarcha, MSc, Raquel Gomez Bris, MSc, Virginia Zorita, MSc, Angela Sáez, PhD, Sanne Lidewij Maas, MSc, Laura Pérez-Olivares, MSc, Andrea Herrero-Cervera, PhD, Patricia Lemnitzer, BSc, Kristof van Avondt, PhD, Carlos Silvestre-Roig, PhD, Jose Maria Gonzalez-Granado, PhD, Raphael Chevre, PhD and Oliver Soehnlein, MD, PhD Chang PanChang Pan Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.). Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.). , Beatriz Herrero-FernandezBeatriz Herrero-Fernandez LamImSys Lab, Instituto de Investigación Sanitaria Hospital), Madrid, Spain (B.H.-F., R.G.B., A.S., J.M.G.-G.). Departamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid (UAM), Spain (B.H.-F., R.G.B.). , Celia Borja AlmarchaCelia Borja Almarcha Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.). Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.). , Raquel Gomez BrisRaquel Gomez Bris LamImSys Lab, Instituto de Investigación Sanitaria Hospital), Madrid, Spain (B.H.-F., R.G.B., A.S., J.M.G.-G.). Departamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid (UAM), Spain (B.H.-F., R.G.B.). , Virginia ZoritaVirginia Zorita Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (V.Z., J.M.G.-G.). , Angela SáezAngela Sáez LamImSys Lab, Instituto de Investigación Sanitaria Hospital), Madrid, Spain (B.H.-F., R.G.B., A.S., J.M.G.-G.). Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria (UFV), Pozuelo de Alarcón, Madrid, Spain (A.S.). , Sanne Lidewij MaasSanne Lidewij Maas Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.). , Laura Pérez-OlivaresLaura Pérez-Olivares Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.). Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.). , Andrea Herrero-CerveraAndrea Herrero-Cervera https://orcid.org/0000-0001-6490-6504 Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.). , Patricia LemnitzerPatricia Lemnitzer Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.). , Kristof van AvondtKristof van Avondt Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.). Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.). , Carlos Silvestre-RoigCarlos Silvestre-Roig Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.). Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.). , Jose Maria Gonzalez-GranadoJose Maria Gonzalez-Granado LamImSys Lab, Instituto de Investigación Sanitaria Hospital), Madrid, Spain (B.H.-F., R.G.B., A.S., J.M.G.-G.). Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain (V.Z., J.M.G.-G.). Department of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Spain (J.M.G.-G.). CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain (J.M.G.-G.). , Raphael ChevreRaphael Chevre https://orcid.org/0000-0002-7564-2919 Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.). Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.). and Oliver SoehnleinOliver Soehnlein Correspondence to: Oliver Soehnlein, MD, PhD, or Raphael Chevre, PhD, Institute of Experimental Pathology (ExPat), Westfälische Wilhelms-Universität (WWU), Von Esmarch Str 56, 48149 Münster, Germany. Email E-mail Address: [email protected] or E-mail Address: [email protected] https://orcid.org/0000-0002-7854-0694 Institute of Experimental Pathology (ExPat), Center for Molecular Biology of Inflammation (ZMBE), Westfälische Wilhelms-Universität (WWU), Münster, Germany (C.P., C.B.A., L.P.-O. A.H.-C., K.v.A., C.S.-R., R.C., O.S.). Institute for Cardiovascular Prevention (IPEK), Ludwig Maximilian University, Munich, Germany (C.P., C.B.A., S.L.M., L.P.-O., P.L., K.v.A., C.S.-R., R.C., O.S.). Department of Physiology and Pharmacology (FyFa), Karolinska Institute, Stockholm, Sweden (O.S.). Originally published27 Feb 2023https://doi.org/10.1161/CIRCULATIONAHA.122.063184Circulation. 2023;147:774–777Footnotes*R. Chevre and O. Soehnlein contributed equally.For Sources of Funding and Disclosures, see pages 776–777.Circulation is available at www.ahajournals.org/journal/circCorrespondence to: Oliver Soehnlein, MD, PhD, or Raphael Chevre, PhD, Institute of Experimental Pathology (ExPat), Westfälische Wilhelms-Universität (WWU), Von Esmarch Str 56, 48149 Münster, Germany. Email [email protected]de or raphael.[email protected]deReferences1. Chaix A, Manoogian ENC, Melkani GC, Panda S. Time-restricted eating to prevent and manage chronic metabolic diseases.Annu Rev Nutr. 2019; 39:291–315. doi: 10.1146/annurev-nutr-082018-124320CrossrefMedlineGoogle Scholar2. Chaix A, Lin T, Le HD, Chang MW, Panda S. Time-restricted feeding prevents obesity and metabolic syndrome in mice lacking a circadian clock.Cell Metab. 2019; 29:303–319.e4. doi: 10.1016/j.cmet.2018.08.004CrossrefMedlineGoogle Scholar3. Silvestre-Roig C, Braster Q, Ortega-Gomez A, Soehnlein O. 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Artery-associated sympathetic innervation drives rhythmic vascular inflammation of arteries and veins.Circulation. 2019; 140:1100–1114. doi: 10.1161/CIRCULATIONAHA.119.040232LinkGoogle Scholar Previous Back to top Next FiguresReferencesRelatedDetails February 28, 2023Vol 147, Issue 9 Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCULATIONAHA.122.063184PMID: 36848415 Originally publishedFebruary 27, 2023 Keywordsatherosclerosishypercholesterolemiadiet, high-fatnon-alcoholic fatty liver diseaseintermittent fastingPDF download Advertisement SubjectsAtherosclerosis