疾病
线粒体
糖尿病
癌症
医学
生物信息学
基因组学
心脏病
阿尔茨海默病
线粒体DNA
冠心病
老年学
生物
内科学
遗传学
内分泌学
基因组
基因
标识
DOI:10.1097/jxx.0000000000000880
摘要
ABSTRACT Many things are associated with decreased health and lifespan, including cancer, diabetes, atherosclerosis, high blood pressure, and chronic inflammatory conditions. Clinicians may not be familiar with the role that mitochondrial mutations and associated mitochondrial dysfunction play in a shortened lifespan. This article, the fifth in the JAANP Genomics of Aging series, describes the role that mitochondrial dysfunction plays in the development of age-related diseases such as Alzheimer disease, Parkinson disease, cancer, heart disease, and stroke.
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