尿酸
检出限
电化学气体传感器
计时安培法
可穿戴计算机
材料科学
线性范围
化学
生物医学工程
电极
电化学
色谱法
医学
生物化学
计算机科学
循环伏安法
嵌入式系统
物理化学
作者
Zhanhong Li,Yuwei Wang,Zhixing Fan,Youhong Sun,Yan Sun,Yi Yang,Yifan Zhang,Junjie Ma,Zifeng Wang,Zhigang Zhu
出处
期刊:Biosensors
[MDPI AG]
日期:2023-01-06
卷期号:13 (1): 105-105
被引量:11
摘要
Simultaneous detection of uric acid and glucose using a non-invasive approach can be a promising strategy for related diseases, e.g., diabetes, gout, kidney disease, and cardiovascular disease. In this study, we have proposed a dual-function wearable electrochemical sensor for uric acid and glucose detection in sweat. The sensor with a four-electrode system was prepared by printing the ink on a common rubber glove. CV and chronoamperometry were used to characterize the prepared sensor's electrochemical sensing performance. The sensors exhibited the linear range from 0 to 1.6 mM and 0 to 3.7 mM towards uric acid and glucose electrochemical sensing in phosphate-buffered solution, with the corresponding limit of detection of 3.58 μM and 9.10 μM obtained, respectively. Moreover, the sensors had shown their feasibility of real sample sensing in sweat. The linear detection range for uric acid (0 to 40 μM) and glucose (0 to 1.6 mM) in the sweat can well cover their concentration range in physiological conditions. The prepared dual-function wearable electrochemical sensor features easy preparation, fast detection, high sensitivity, high selectivity, and the practical application potential in uric acid and glucose sensing.
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