Modeling of the Lipid Bilayer Mimicking the Inner Mitochondrial Membrane

The model of the lipid bilayer mimicking the inner mitochondrial membrane was constructed. Each layer of the lipid bilayer model consists of 51 dilinoleoyl phosphatidylethanolamine molecules, 36 dilinoleoyl phosphatidylcholine molecules, 35 tetraoleoyl cardiolipin molecules, and 6 dilinoleoyl phosphatidylinositol molecules. This model was analyzed by molecular dynamics simulation (20 000 ps). The mobility of different lipids and groups of atoms involved in the lipids is described. This model can be used to study the lipid component of the inner mitochondrial membrane.