Paper deals with characterization of gypsum, its calcination to β-hemihydrate plaster, chemistry and constitution, setting and expansion. Configuration of Bhutanese gypsum plant and production of gypsum plaster by the process suggested by CBRI vis-a-vis to process adopted by the plant have been explained. Gypsum at 180°C with 1 h retention time gave plaster of better setting and strength properties acceptable to market complying relevant standards.