依那西普
日本脑炎
医学
免疫学
神经炎症
病毒性脑炎
肿瘤坏死因子α
黄病毒
脑炎
自身免疫性脑炎
中枢神经系统
炎症
病毒
病毒学
内科学
作者
Jing Ye,Rong Jiang,Min Cui,Bibo Zhu,Leqiang Sun,Yue-Yun Wang,Ali Zohaib,Qian Dong,Xindi Ruan,Yinglin Song,He Wen,Huanchun Chen,Shengbo Cao
标识
DOI:10.1093/infdis/jiu179
摘要
Background. Japanese encephalitis virus (JEV) is a neurotropic flavivirus that causes Japanese encephalitis (JE), which leads to high fatality rates in human. Tumor necrosis factor alpha (TNF-α) is a key factor that mediates immunopathology in the central nervous system (CNS) during JE. Etanercept is a safe anti-TNF-α drug that has been commonly used in the treatment of various human autoimmune diseases.
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