New neolignans and lignans from the aril of Myristica fragrans

Eight neolignans and five lignans were isolated from mace, the aril of Myristica fragrans, and their structures were determined by spectroscopic methods aserythro-2-(4″-allyl-2″,6″-dimethoxyphenoxy)-1-(3′,4′,5′-trimethoxyphenyl)propan-1,3-diol (1b),threo-2-(4″-allyl-2″-methoxyphenoxy)-1-(4′-hydroxy-3′-methoxyphenyl) propan-1-ol (2a),threo-1-(4′-hydroxy-3′-methoxyphenyl)-2-(2″-methoxy-4″-(1‴ (E)-propenyl) phenoxy) propan-1-ol (3a), itserythro form (3b),threo-1-(4′-hydroxy-3′-methoxyphenyl)-1-methoxy-2-(2″-methoxy-4″-(1‴-(E)-propenyl)phenoxy)-propane (4a), itserythro form (4b), fragransol-A (5), fragransol-B (6), fragransin D1 (7), fragransin D2 (8), fragransin D3 (9), fragransin E1 (10) and the known compound austrobailignan-7 (11).