敏化
肿瘤微环境
癌症研究
免疫疗法
免疫检查点
免疫系统
封锁
免疫学
医学
化学
生物
受体
内科学
作者
Rachael M. Zemek,Emma de Jong,Wee Loong Chin,Iona S. Schuster,Vanessa S. Fear,Thomas H. Casey,Cath Forbes,Sarah Dart,Connull Leslie,Ayham Zaitouny,Michael Small,Louis Boon,Alistair R.R. Forrest,Daithi O. Muiri,Mariapia A. Degli-Esposti,Michael Millward,Anna K. Nowak,Timo Lassmann,Anthony Bosco,Richard Lake,W. Joost Lesterhuis
出处
期刊:Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期:2019-07-17
卷期号:11 (501)
被引量:131
标识
DOI:10.1126/scitranslmed.aav7816
摘要
A STAT1-driven inflammatory phenotype associated with response to checkpoint blocking antibodies sensitizes cancers to immunotherapy.
科研通智能强力驱动
Strongly Powered by AbleSci AI