Chemotherapy-Induced Peripheral Neuropathy: Association With Increased Risk of Falls and Injuries

BACKGROUND: Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating and degenerative side effect of many commonly used chemotherapy agents. Symptoms manifest as sensory and motor neuropathies. CIPN may necessitate chemotherapy dose reduction or discontinuation. OBJECTIVES: This review intends to summarize literature linking CIPN to an increased risk of falls and injuries and provides recommendations to help maintain patient safety and maximize physical function. METHODS: A literature search was conducted using MEDLINE®, PubMed®, and ScienceDirect. FINDINGS: Assessment of CIPN and CIPN-related falls and injuries is vital in preventing related complications, and proper education of oncology nursing staff on CIPN assessment and management is necessary.