The Clinical Analysis of 30 Patients with Severe Acute Pancreatitis Treated by Somatostatin

Objective: The observe the clinical efficacy of somatostatin in treatment of severe acute pancreatitis. Methods: 30 patients with severe acute pancreatitis hospitalized from Aug 2001 to Aug 2004 were treated by forbidding food, decompressing stomach and intestines, and were injected with somatostatin 250 μg firstly and continuously injected at the rate of 250 μg/min for 7～14 days. The disappearance of symptoms and abdominal signs, amylase of urine and blood, the time of recovery of hepatic function were observed. Results: The total efficacy rate was 85%. Conclusions: Somatostatin is effective in treating severe acute pancreatitis,and there is no obvious side effect.