Objective To analyze the surveillance results of outbreaks of influenza-like illness(ILI) in Shenzhen from 2010 to 2011,to know the epidemic trend of ILI,and to provide a scientific basis for ILI prevention and treatment. Methods The study was conducted on the surveillance data of ILI outbreaks in Shenzhen from 2010 to 2011. Results A total of 226 ILI outbreaks were reported in Shenzhen from 2010 to 2011.2,026 cases of ILI were identified during the outbreaks,with the average incidence rate of 14.2%.64 ILI outbreaks were reported in December,followed by 56 outbreaks in March and 39 outbreaks in April.201 out of 226 outbreaks were tested positive for influenza,consisting of 171 outbreaks for type B(85.0%),17 outbreaks for novel H1N1(8.5%),and 13 outbreaks for seasonal type A(6.5%). Conclusions The intensity of influenza circulation was medium during the period of 2010-2011,and the peak of influenza activity occurred in March,April and December.