The characteristics and the chemical reactions of the hydroxyl radical in water, the reaction pathways leading to the generation of ·OH in advanced oxidation process, O_3/UV,O_3/H_2O_2,H_2O_2/UV,UV/O_3/H_2O_2,H_2O_2/Fe~(2+)(Fenton's reagent),H_2O_2/Fe~(2+)/UV, Electro-Fenton and heterogeneous photoatalysis oxidation have been reviewed in this paper.