Objective To analyze the morbidity of liver cancer and viral hepatitis B from 1988 to 2010 at Ninghe County in Tianjin.Methods The report date of the incidence of liver cancer and hepatitis B from 1988 to 2010 at County Ninghe were collected.The crude and standardized morbidity rate(SMR)was calculated.Results The SMR of liver cancer from 1988 to 2010 at County Ninghe was 22.43/100 000,which was nearly twice as much as the average level of liver cancer incidence(10.22/100 000)in Tianjin.The peak SMR was located at year 1990 to 2006,and then it declined.The incidence of hepatitis B was 2/100 000 in 1990 and it reached to the peak value of 43/100 000 in 2006.After vaccination against hepatitis B for whole residents at Ninghe county from January 2008 to September 2010,the incidence of hepatitis B in 2010 decreased by 36.2% than that in 2007.The rate in peasants dropped by 32.8%,the rate in students dropped by 22.2% and the rate in government staff dropped by 76.9%.The incidence of hepatitis B in government staff and students were lower than 1/100 000 and 4/100 000,respectively.Conclusion The incidence of liver cancer at Ninghe County was higher than the average level of Tianjin.The incidences of liver cancer and hepatitis B declined from 2007.