医学
肠道通透性
发病机制
炎症
免疫系统
磁导率
胃肠病学
内科学
免疫学
生物化学
生物
膜
作者
Yuyao Wu,Zishao Zhong,Zhenhao Ye,Wang Zhang,Guihua He,Yifeng Zheng,Suiping Huang
摘要
Background: Functional dyspepsia (FD) is a gastrointestinal disease caused by imbalanced gastrointestinal function. Traditional treatments are deemed to be limited, and new therapeutic drugs are required. New study suggested that duodenal low-grade inflammation and increased intestinal permeability play an important role in the pathogenesis of FD. Previous studies have shown that polysaccharides containing D-galacturonic acid (GA) could modulate intestinal immune activity in vitro and in animal models. However, the ability of GA monomer to improve intestinal mucosal permeability and inflammation in FD has not been clearly elucidated.
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