Radical Addition-Triggered Remote Migratory Isomerization of Unactivated Alkenes to Difluoromethylene-Containing Alkenes Enabled by Bimetallic Catalysis

A fascinating alkene remote migratory isomerization engendered by carbon radical addition to C═C bond in alkenes via bimetallic catalysis has been disclosed. A diverse array of alkenes bearing distantly incorporated the difluoromethylene (RCF2R′) functionality have been expediently obtained. The retainment of C═C bonds in products could serve as an useful synthetic platform furnishing otherwise difficult to access value-added densely functionalized RCF2R′-containing molecules. In addition, some experimental studies have been implemented to shed light on the probable mechanism.