材料科学
腐蚀
模拟体液
扫描电子显微镜
溅射沉积
化学工程
涂层
合金
傅里叶变换红外光谱
表面改性
溅射
电化学
冶金
复合材料
纳米技术
薄膜
化学
工程类
电极
物理化学
作者
Ana-Iulia Biță,Iulian Antoniac,Marian Miculescu,George E. Stan,Lucia Leonat,Aurora Antoniac,Bujor Constantin,Norina Consuela Forna
出处
期刊:Materials
[Multidisciplinary Digital Publishing Institute]
日期:2022-04-25
卷期号:15 (9): 3100-3100
被引量:24
摘要
The use of resorbable magnesium alloys in the design of implants represents a new direction in the healthcare domain. Two main research avenues are currently explored for developing or improving metallic biomaterials: (i) increase of their corrosion resistance by designed compositional and structural modifications, and (ii) functionalization of their surfaces by coating with ceramic or polymeric layers. The main objective of this work was to comparatively assess bio-functional coatings (i.e., highly-crystallized hydroxyapatite and silica-rich glass) deposited by radio-frequency magnetron sputtering (RF-MS) on a biodegradable Mg-0.8Ca alloy (0.8 wt.% of Ca). After probing their morphology (by scanning electron microscopy) and structure (by Fourier transform infrared spectroscopy and grazing incidence X-ray diffraction), the corrosion resistance of the RF-MS coated Mg-0.8Ca substrates was electrochemically tested (in synthetic biological media with different degrees of biomimicry), and their cytocompatibility was assessed in osteoblast and fibroblast cell cultures. By collective assessment, the most promising performances, in terms of mass loss (~7% after 12 days), hydrogen release rate (~6 mL/cm2 after 12 days), electrochemical corrosion parameters and cytocompatibility, were obtained for the crystalline HA coating.
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