Facile and fast synthesis of three-dimensional Ce-MOF/Ti3C2TX MXene composite for high performance electrochemical sensing of L-Tryptophan

Rational design and constructed new electrode material as high performance electrochemical sensor with outstanding selectivity, reproducibility and stability is an urgent demand for trace detection. Herein, a novel Ce-MOF/Ti3C2TX MXene composite as electrochemical sensor for L-Tryptophan (L-Trp) was constructed by utilizing the three-dimensional straw-sheaf-like Ce-MOF and Ti3C2TX MXene nanosheets. The combination of Ce-MOF and Ti3C2TX MXene not only significantly improves the conductivity of metal-organic framework (MOF) but also effectively prevents the stacking of Ti3C2TX MXene nanosheets. The electrochemical properties of the proposed sensor were investigated by electrochemical techniques in detail. The L-Trp sensor exhibits a wide linear range (0.2 ​μM–139 ​μM) and a low limit of detection (0.19 ​μM, S/N ​= ​3). Moreover, the proposed sensor exhibits excellent selectivity, good reproducibility and long-term stability, as well as satisfactory practical ability in real blood serum samples.