重编程
生物
细胞生物学
干细胞
计算生物学
细胞
类有机物
电池类型
细胞命运测定
胚胎干细胞
细胞分化
遗传学
转录因子
基因
作者
Yu Fu,Yuanyue Shan,Mingfeng Zhang,Duanqing Pei
出处
期刊:Cell Stem Cell
[Elsevier BV]
日期:2021-10-01
卷期号:28 (10): 1677-1678
标识
DOI:10.1016/j.stem.2021.09.012
摘要
How master regulators such as Oct4 can shape 3D genome architecture during cell reprogramming remains poorly understood. In this issue of Cell Stem Cell, Wang et al. (2021) demonstrate that Oct4 undergoes phase separation to reconfigure TAD architecture for cell fate control.
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