活性氧
毒性
程序性细胞死亡
生物分子
纳米技术
化学
细胞生物学
生物
材料科学
细胞凋亡
生物化学
有机化学
作者
An Xie,He Li,Yushu Hao,Yujia Zhang
标识
DOI:10.1186/s11671-021-03599-8
摘要
Abstract The biological functions and toxic effects of reactive oxygen species (ROS) are generally entangled. A large amount of ROS may cause oxidative damage to cell biomolecules, leading to cell death. Tumor treatment can be carried out by using the toxicity of ROS, and various nanosystems related to ROS have been designed. In fact, the level of active oxygen in the biological microenvironment can be regulated in advanced therapeutics via designed nanoscale engineering, which can open up a new direction of treatment with specific simplicity. In this progress report, the authors first introduced how ROS causes cell death. Then, recent studies on converting the inherent toxicity from ROS into advanced treatment tools are highlighted.
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