生物
癌症研究
滤泡性淋巴瘤
Notch信号通路
遗传学
外显子组测序
种系突变
突变
基因
淋巴瘤
免疫学
作者
Kilannin Krysiak,Felicia Gomez,Brian S. White,Matthew K. Matlock,Christopher A. Miller,Lee Trani,Catrina C. Fronick,Robert S. Fulton,Friederike Kreisel,Amanda F. Cashen,Kenneth R. Carson,Melissa M. Berrien-Elliott,Nancy L. Bartlett,Malachi Griffith,Obi L. Griffith,Todd A. Fehniger
出处
期刊：Blood
[Elsevier BV]
日期：2016-11-14
卷期号：129 (4): 473-483
被引量：180
标识
DOI：10.1182/blood-2016-07-729954
摘要
Key Points FLs harbor more recurrent mutations in the BCR signaling pathway, SWI/SNF complex, and histone genes than previously known. Novel recurrent mutations affecting BTK, SYK, and HVCN1 may have therapeutic and prognostic implications for FL.
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