益生菌
微生物群
封装(网络)
肠道微生物群
材料科学
胃肠道
纳米技术
细菌
生物
生物信息学
计算机科学
生物化学
计算机网络
遗传学
作者
Aaron C. Anselmo,Kevin J. McHugh,Jamie Webster,Róbert Langer,Ana Jaklenec
标识
DOI:10.1002/adma.201603270
摘要
The gastrointestinal (GI) microbiome is widely investigated for its role in many diseases. However, technologies designed for microbiome delivery are lacking. Here, a layer-by-layer (LbL) approach is reported for probiotic encapsulation to protect probiotics against GI tract insults and improve their adhesion and growth on the intestines. These advantages translate to significantly enhanced survival of LbL-probiotics in vivo.
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