The cabin pressurization system response should be consistent with the design limits such as the cabin pressure schedule, the pressure regulation tolerance, the maximum rate of pressure change during normal and abnormal operation and the maximum cabin air inflow rate change. In this paper, the results of pressure loss analysis and flight test for cabin pressurization system of T-50 advanced trainer are introduced. The pressure tolerance at unpressurized condition using calculated exit area of pressurization components through pressure loss analysis is predicted. Pressurization components of D company are selected and the predicted pressure tolerance is in good agreement with flight test results. Finally, T-50 pressurization system is verified by some flight tests of T-50 advanced trainer to comply with various pressurization design criteria of MIL-E-18927.