组织扩张
生物相容性
自愈水凝胶
肿胀 的
生物相容性材料
生物医学工程
共聚物
体积膨胀
膨胀率
组织工程
材料科学
渗透压
复合材料
化学工程
化学
高分子化学
聚合物
外科
生物化学
冶金
工程类
内科学
医学
标识
DOI:10.1016/s1010-5182(05)80353-1
摘要
The possibility of using an osmotically-driven system for effective tissue expansion has been verified. As a biocompatible and efficient system, a copolymer of methylmethacrylate and vinylpyrrolidone is used in animal research (rats). This hydrogel was able to generate, in vitro, a physical swelling pressure of approximately 235 mm Hg. The range of possible volume expansion in solutions of differing concentrations was 3 to 30 times its water-free gel form. In animal experiments a high biocompatibility and efficiency in tissue expansion can be observed.
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