A Direct Synthesis of Vinylic Phosphonates from Vinylic Halides

Abstract Approaches to the formation of vinylic phosphonates through direct replacement of a vinylic halide by phosphorus have received considerable attention. With the exception of α,β-unsaturated systems1,2 attempts involving simple Michaelis-Arbuzov reaction conditions (heating, trivalent phosphorus ester) have failed.3–5 Other efforts involving transition metal salts as catalysts have found greater, but still quite limited success.6–8