路易斯酸
化学
密度泛函理论
生物催化
基础(拓扑)
绿色化学
组合化学
超分子化学
计算化学
催化作用
反应机理
有机化学
分子
数学
数学分析
作者
Yan Liu,Qiwu Yang,Dongling Hao,Wenqin Zhang
摘要
An efficient method for triarylmethanimine synthesis promoted by a Lewis acid–base pair (AlCl3–Et3N) was designed using mechanistic analysis with the aid of density functional theory. A series of triarylmethanimines were successfully prepared under mild conditions in good to excellent yields with a simple work-up procedure. The promoter, the Lewis acid–base pair (AlCl3–Et3N), is inexpensive, efficient, and shows good functional group tolerance. The experimental results show that the electronic effect played a significant role, i.e. the reactions proceeded smoothly when electron-sufficient arylamines and electron-deficient ketones were used as substrates.
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