化学
乙酰丙酮
糠醛
Knoevenagel冷凝
羟醛缩合
苯甲醛
丙酮
有机化学
区域选择性
产量(工程)
冷凝
硼
催化作用
冶金
材料科学
物理
热力学
作者
Val V. Martichonok,Peter K. Chiang,Padraick J. Dornbush,Kirkwood M. Land
标识
DOI:10.1080/00397911.2013.850094
摘要
Abstract While cinnamoyl acetone 1 is obtained in good yield by a condensation of 3 molar excess of a borate complex of acetylacetone with benzaldehyde, products of Knoevenagel condensation 2 are predominantly obtained with furfural and 5-substituted furfurals. Cinnamoyl acetone 1 can be further condensed with furfural to form unsymmetrical curcuminoid 5. Compound 2a does not produce any new products under the same conditions. Compounds 3 and 5 are good inhibitors of growth of protozoan Trichomonas vaginalis.
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