Non-mesenchymal Mimics of Sarcoma

A variety of different non-mesenchymal neoplasms may mimic sarcoma, in particular sarcomatoid carcinoma and melanoma, but also mesothelioma and rarely some lymphomas. This article reviews the key clinical and histologic features of such neoplasms in different settings, along with the use of ancillary studies to help identify the tumor types most frequently misdiagnosed as sarcoma.