MgSiO3 NPs catalyzed intramolecular cycloaddition reaction: A simple and stereoselective synthesis of unprecedented julolidine analogs

A new julolidine hybrid analogs have been accomplished in a regio and stereo controlled manner using heterogenous MgSiO3 nanoparticles (NPs) catalyzed intramolecular dipolar cycloaddition reaction as a key step. The synthesized catalyst was used in the preparation of various new julolidine analogs with a good yield ranging from 65 to 85%. Further, catalyst could be recycled in several times without loss of significant activity which was an added advantage to the principles of green chemistry.