Two New Steroidal Saponins from the Processed Polygonatum kingianum

Abstract Two new spirostanol saponins, kingianoside I ( 1 ) and kingianoside K ( 2 ), corresponding to (3 β ,23 S ,25 R )‐23‐hydroxy‐12‐oxospirost‐5‐en‐3‐yl 4‐ O ‐ β ‐ D ‐glucopyranosyl‐ β ‐ D ‐galactopyranoside ( 1 ) and (3 β ,25 R )‐7‐oxospirost‐5‐en‐3‐yl α ‐ L ‐arabinofuranosyl‐(1→4)‐[6‐deoxy‐ α ‐ L ‐mannopyranosyl‐(1→2)]‐ β ‐ D ‐glucopyranoside ( 2 ), along with 13 known compounds, daucosterol, (25 R )‐kingianoside G, (25 RS )‐kingianoside A, pratioside D 1 , (25 RS )‐pratioside D 1 , (25 S )‐kingianoside C, kingianoside C, ginsenoside Rb 1 , saponins Tb and Pb, dioscin, gracillin, and saponin Pa, were isolated from the processed rhizomes of Polygonatum kingianum. The structures of the new compounds were elucidated by detailed spectroscopic analyses, including 1D‐ and 2D‐NMR techniques, and chemical methods. Compound 2 contains a novel unusual spirostanol saponin aglycone. Ginsenoside Rb 1 and saponin Tb were isolated for the first time from the genus Polygonatum. The 13 known compounds were detected for the first time in the processed Polygonatum kingianum.