Overexpression of Ku80 Protects Lens Epithelial Cells from Selenium-Induced Cataract Formation by Regulating the DNA Damage Response

Ku80 overexpression alleviates damage to LECs and postpones the development of selenium-induced cataracts by increasing CSB protein levels and controlling DNA repair processes. This research underscores the significant therapeutic potential of Ku80 in postponing cataract formation and may offer new avenues for gene therapy in the prevention and treatment of cataracts.