In Utero and Early-Childhood Exposure to the Great Chinese Famine and Adult Arterial Stiffness: A Cross-Sectional Study

HomeArteriosclerosis, Thrombosis, and Vascular BiologyVol. 44, No. 3In Utero and Early-Childhood Exposure to the Great Chinese Famine and Adult Arterial Stiffness: A Cross-Sectional Study No AccessResearch ArticleRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessResearch ArticleRequest AccessFull TextIn Utero and Early-Childhood Exposure to the Great Chinese Famine and Adult Arterial Stiffness: A Cross-Sectional Study Shouling Wu, Xiujuan Zhao, Lu Li, Xu Han, Qian Liu, Shuohua Chen, Hemei Geng, Hannah VanEvery and Xinyuan Zhang Shouling WuShouling Wu Correspondence to: Shouling Wu, MD, Department of Cardiology, Kailuan General Hospital, 57 Xinhua E Rd, Tangshan 063000, China, Email E-mail Address: [email protected] https://orcid.org/0000-0001-7095-6022 Department of Cardiology (S.W., X. Zhao, L.L., X.H., Q.L., S.C.), Kailuan General Hospital, Tangshan, China. , Xiujuan ZhaoXiujuan Zhao Department of Cardiology (S.W., X. Zhao, L.L., X.H., Q.L., S.C.), Kailuan General Hospital, Tangshan, China. , Lu LiLu Li Department of Cardiology (S.W., X. Zhao, L.L., X.H., Q.L., S.C.), Kailuan General Hospital, Tangshan, China. , Xu HanXu Han Department of Cardiology (S.W., X. Zhao, L.L., X.H., Q.L., S.C.), Kailuan General Hospital, Tangshan, China. , Qian LiuQian Liu https://orcid.org/0009-0003-6722-6653 Department of Cardiology (S.W., X. Zhao, L.L., X.H., Q.L., S.C.), Kailuan General Hospital, Tangshan, China. , Shuohua ChenShuohua Chen https://orcid.org/0000-0002-6274-7471 Department of Cardiology (S.W., X. Zhao, L.L., X.H., Q.L., S.C.), Kailuan General Hospital, Tangshan, China. , Hemei GengHemei Geng Hospital Infection Management Division (H.G.), Kailuan General Hospital, Tangshan, China. , Hannah VanEveryHannah VanEvery https://orcid.org/0000-0002-0778-0607 Department of Medicine, University of Pittsburgh, PA (H.V.). and Xinyuan ZhangXinyuan Zhang Xinyuan Zhang, PhD, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Room 450G, 181 Longwood Ave, Boston, MA 02115, Email E-mail Address: [email protected] https://orcid.org/0000-0002-2974-8392 Department of Nutrition, Pennsylvania State University, University Park, TX (X. Zhang). Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (X. Zhang). Originally published1 Feb 2024https://doi.org/10.1161/ATVBAHA.124.320666Arteriosclerosis, Thrombosis, and Vascular Biology. 2024;44:755–757FootnotesFor Sources of Funding and Disclosures, see page 757.Correspondence to: Shouling Wu, MD, Department of Cardiology, Kailuan General Hospital, 57 Xinhua E Rd, Tangshan 063000, China, Email drwusl@163.comXinyuan Zhang, PhD, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Room 450G, 181 Longwood Ave, Boston, MA 02115, Email hpxzh@channing.harvard.eduREFERENCES1. Li Y, Li Y, Gurol ME, Liu Y, Yang P, Shi J, Zhuang S, Forman MR, Wu S, Gao X. In utero exposure to the Great Chinese famine and risk of intracerebral hemorrhage in midlife.Neurology. 2020; 94:e1996–e2004. doi: 10.1212/WNL.0000000000009407CrossrefMedlineGoogle Scholar2. Painter RC, de Rooij SR, Bossuyt PM, de Groot E, Stok WJ, Osmond C, Barker DJ, Bleker OP, Roseboom TJ. Maternal nutrition during gestation and carotid arterial compliance in the adult offspring: the Dutch famine birth cohort.J Hypertens. 2007; 25:533–540. doi: 10.1097/HJH.0b013e328012135bCrossrefMedlineGoogle Scholar3. Rotar O, Moguchaia E, Boyarinova M, Kolesova E, Khromova N, Freylikhman O, Smolina N, Solntsev V, Kostareva A, Konradi A, et al. Seventy years after the siege of Leningrad: does early life famine still affect cardiovascular risk and aging?J Hypertens. 2015; 33:1772–1779; discussion 1779. doi: 10.1097/HJH.0000000000000640CrossrefMedlineGoogle Scholar4. Zhang X, Wang G, Forman MR, Fu Q, Rogers CJ, Wu S, Gao X. In utero and childhood exposure to the great Chinese famine and risk of cancer in adulthood: the Kailuan study.Am J Clin Nutr. 2021; 114:2017–2024. doi: 10.1093/ajcn/nqab282CrossrefMedlineGoogle Scholar5. Zheng M, Zhang X, Chen S, Song Y, Zhao Q, Gao X, Wu S. Arterial stiffness preceding diabetes: a longitudinal study.Circ Res. 2020; 127:1491–1498. doi: 10.1161/CIRCRESAHA.120.317950LinkGoogle Scholar Previous Back to top Next FiguresReferencesRelatedDetails March 2024Vol 44, Issue 3 Advertisement Article InformationMetrics © 2024 American Heart Association, Inc.https://doi.org/10.1161/ATVBAHA.124.320666PMID: 38299354 Originally publishedFebruary 1, 2024 Keywordscardiovascular diseasesnutritional statusrisk factorsvascular stiffnessPDF download Advertisement SubjectsDiet and NutritionRisk FactorsVascular Disease