Surface Functionalization Based on Protein Amyloid-like Aggregation★

Surface modification plays a pivotal role across various domains by conferring novel properties and heightened value to materials, all while preserving their inherent characteristics.However, a critical impediment stalling the broader utilization and advancement of advanced interface materials is the absence of a simple, environmentally friendly, universally applicable, colorless and transparent interface modification system.Since the initial reports of employing amyloid-like proteins for interface modification, this approach has garnered considerable attention and research within the academic community.Subsequently, an array of protein-based materials featuring diverse morphological structures such as nanofilms, nanofibers, large particle aggregates, hydrogels, aerogels, and more have emerged.This review commences by elucidating the fundamental principles underlying amyloid-like protein aggregation.Subsequently, it provides a comprehensive summary of its applications as a surface modification system in various domains including biomedical coatings, separation and dialysis, biomineralization, flexible electronics, smart fabrics, chemical catalysis and environmental pollutant removal.Furthermore, it discusses the current application directions and ultimately highlights the system's limitations, concluding with a prospective outlook on its future development.