医学
糖尿病
安普克
纤维化
EZH2型
心肌纤维化
信号转导
内科学
生物信息学
内分泌学
细胞生物学
蛋白激酶A
组蛋白
磷酸化
生物化学
基因
生物
化学
作者
Shanshan Li,Pan Lu,Zhen‐Ye Zhang,Meng-Dan Zhou,Xufei Chen,Lingling Qian,Min Dai,Juan Lu,Zhi‐Ming Yu,Shipeng Dang,Ruxing Wang
标识
DOI：10.4093/dmj.2023.0031
摘要
Diabetes-induced cardiac fibrosis is one of the main mechanisms of diabetic cardiomyopathy. As a common histone methyltransferase, enhancer of zeste homolog 2 (EZH2) has been implicated in fibrosis progression in multiple organs. However, the mechanism of EZH2 in diabetic myocardial fibrosis has not been clarified.
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