Caveat Emptor: Vasopressor Choice and Postoperative Delirium—A Complex Relationship Explored

Editorial| April 2024 Caveat Emptor: Vasopressor Choice and Postoperative Delirium—A Complex Relationship Explored This article has an Audio Podcast Amy L. Gaskell, M.B.Ch.B., Ph.D., F.A.N.Z.C.A.; Amy L. Gaskell, M.B.Ch.B., Ph.D., F.A.N.Z.C.A. 1Te Whatu Ora – Waikato, Hamilton, New Zealand; and University of Auckland, Auckland, New Zealand. https://orcid.org/0000-0002-7298-0250 Search for other works by this author on: This Site PubMed Google Scholar Douglas Campbell, B.M., F.R.C.A., F.A.N.Z.C.A.; Douglas Campbell, B.M., F.R.C.A., F.A.N.Z.C.A. 2Te Whatu Ora – Auckland, Auckland, New Zealand; and University of Auckland, Auckland, New Zealand. Search for other works by this author on: This Site PubMed Google Scholar Arthur M. Lam, M.D., F.R.C.P.C., F.N.C.S. Arthur M. Lam, M.D., F.R.C.P.C., F.N.C.S. 3University of California, San Diego, San Diego, California; and Virginia Mason Medical Center. Seattle, Washington. Search for other works by this author on: This Site PubMed Google Scholar Author and Article Information This editorial accompanies the articles on pp. 657 and 669. Accepted for publication December 11, 2023. Address correspondence to Dr. Gaskell: Anesthesiology April 2024, Vol. 140, 642–645. https://doi.org/10.1097/ALN.0000000000004876 Connected Content Article: Intraoperative Use of Phenylephrine versus Ephedrine and Postoperative Delirium: A Multicenter Retrospective Cohort Study Article: Cerebral Blood Flow Assessed with Phase-contrast Magnetic Resonance Imaging during Blood Pressure Changes with Noradrenaline and Labetalol: A Trial in Healthy Volunteers Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Search Site Citation Amy L. Gaskell, Douglas Campbell, Arthur M. Lam; Caveat Emptor: Vasopressor Choice and Postoperative Delirium—A Complex Relationship Explored. Anesthesiology 2024; 140:642–645 doi: https://doi.org/10.1097/ALN.0000000000004876 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll PublicationsAnesthesiology Search Advanced Search Topics: postoperative delirium, vasoconstrictor agents The field of perioperative medicine is beset with interesting and promising findings from observational data and preclinical studies, with subsequent failure of translation into robust randomized controlled trial evidence. As a discipline, anesthesia involves the intricate manipulation and maintenance of physiology, counteracting the numerous disruptions induced by our own administration of pharmacologic agents and arising from surgical insults. The meticulous management of blood pressure is a fundamental skill, and to this end, a selection of vasopressors is available, each having different characteristics and effects. So the pivotal question arises: does the choice of vasopressor truly matter? Are there nuances in their selection that significantly affect patient outcomes? Or is the decision merely a matter of convenience? In this issue of Anesthesiology, Ma et al.1 report their findings from a multivariable analysis of a large data set. The retrospective observational study found that phenylephrine use for blood pressure support... You do not currently have access to this content.