BAFFR expression in circulating T follicular helper (CD4+CXCR5+PD-1+) and T peripheral helper (CD4+CXCR5−PD-1+) cells in systemic lupus erythematosus
医学
分子生物学
生物
作者
Nefertari Sagrero‐Fabela,Pablo Cesar Ortiz‐Lazareno,Diana Celeste Salazar‐Camarena,Álvaro Cruz,Sergio Cerpa‐Cruz,José Francisco Muñóz-Valle,Miguel Marín‐Rosales,Jhonatan Antonio Alvarez‐Gómez,Claudia Azucena Palafox‐Sánchez
This study emphasizes the importance of cTfh and Tph cells in SLE pathogenesis. Besides the importance of IL-21, our results suggest that BAFFR could play a role in cTfh and Tph subpopulations in the autoimmunity context.