呋喃西林
光热治疗
检出限
化学
免疫分析
生物芯片
纳米技术
生物相容性
色谱法
材料科学
医学
生物
抗体
有机化学
免疫学
传统医学
作者
Yanli Tian,Xuechi Yin,Huilan Hu,Jiawei Ren,Conghui Jia,Yuechun Li,Jie Sun,Jianlong Wang,Daohong Zhang
出处
期刊:Food Chemistry
[Elsevier]
日期:2023-03-01
卷期号:404: 134686-134686
被引量:4
标识
DOI:10.1016/j.foodchem.2022.134686
摘要
Immunochromatographic assay platforms are up-and-coming detection tools for disease diagnosis and harmful substances monitoring in food. Herein, by combining photothermal imaging and immunochromatographic analysis, a photothermal immunoassay is developed for the rapid and ultrasensitive detection of nitrofurazone. The nickel disulfide nanosphere with excellent biocompatibility, biodegradability, and high photothermal conversion efficiency, is introduced to offer straightforward readout by color and temperature based on the nature of the crystal, without advanced equipment. It is demonstrated that the nitrofurazone metabolite of semicarbazide can be qualitatively detected by colorimetric signals with a visual limit of 2 μg kg-1. And the quantitative detection limit of photothermal signals is 0.01 μg kg-1, improving the detection sensitivity by about 200 times. Furthermore, recovery rates of the proposed method in food samples were 93 %-120 %. This photothermal immunoassay not merely provides straightforward, rapid, simultaneous qualitative/quantitative detection tactics but may also be valuable in automated and portable diagnostic applications.
科研通智能强力驱动
Strongly Powered by AbleSci AI