医学
会阴切开术
随机对照试验
荟萃分析
科克伦图书馆
相对风险
产科
分娩
入射(几何)
置信区间
梅德林
奇纳
外科
怀孕
内科学
心理干预
护理部
法学
政治学
物理
光学
生物
遗传学
作者
Qiuyu Yang,Xiao Cao,Shiqian Hu,Mingyao Sun,Honghao Lai,Liangying Hou,Qi Wang,Cailiang Wu,Wu Y,Xiao Lin,Xiaofeng Luo,Jinhui Tian,Long Ge,Lei Shi
摘要
Abstract Aim To assess the effect of lubricants on reducing perineal trauma during vaginal delivery. Methods PubMed, Embase, the Cochrane Library, CINAHL, China National Knowledge Infrastructure, China Biology Medicine disc, WanFang databases, and ClinicalTrials.gov , were searched for literature up to 25 June 2021. Randomized controlled trials published in English or Chinese that compared the vaginal application of lubricant with standard care for women were included. Two reviewers independently performed study screening, data extraction, risk of bias assessment, and certainty of evidence assessment. Pooled effect sizes and corresponding 95% confidence intervals (CI) were calculated using meta‐analysis. Results Nineteen trials enrolling 5445 pregnant women were included. Compared with standard care, women using lubricants had a lower incidence of perineal trauma (risk ratio [RR] 0.84, 95% CI 0.76–0.93; low certainty evidence), second‐degree perineal laceration (RR 0.72, 95% CI 0.64–0.82; moderate certainty evidence) and episiotomy (RR 0.77, 95% CI 0.62–0.96; very low certainty evidence), and had a shorter duration of the second‐stage labor (MD −13.72 min, 95% CI −22.68 to −4.77; very low certainty evidence). Conclusion Lubricants might reduce the incidence of perineal trauma, especially second‐degree perineal laceration, and shorten the duration of the second‐stage labor. More well‐designed studies will continue developing high‐quality evidence in this field.
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