薯蓣皂甙元
发酵
生化工程
化学
生物技术
计算机科学
环境科学
制浆造纸工业
工程类
有机化学
生物
作者
Xinxin Zhang,Yu Zhang,Yuting Guo,Peiyun Xue,Zhaowei Xue,Yan Zhang,Hong Zhang,Yoichiro Ito,Jun Dou,Zengjun Guo
出处
期刊:Steroids
[Elsevier]
日期:2023-04-01
卷期号:192: 109181-109181
被引量:4
标识
DOI:10.1016/j.steroids.2023.109181
摘要
Diosgenin was the starting materials to synthesize various hormone drugs and mainly generated from Dioscorea zingiberensis C. H. Wright by acidolysis, enzymolysis, microbiological fermentation, and integrated manner. Only acidic hydrolysis with strong acid such as hydrochloric acid or sulfuric acid was used in practice in diosgenin enterprises due to their feasibility and simplicity, nevertheless finally resulting in a great deal of unmanageable wastewater and severely polluted the surrounding environment. Aiming to provide a comprehensive and up-to date information of researches on diosgenin production from this plant, 151 cases were collected from scientific databases including Web of Science, Pubmed, Science Direct, Wiley, Springer, and China Knowledge Resource Integrated (CNKI). Their advantages and disadvantages with different production methods were analyzed based on these available data in this review paper. Considering the fact that nearly all of diosgenin enterprises were closed for the environmental protection and the life health of the people, this review paper was beneficial for providing useful guidelines to develop novel technologies with environmentally-friendly and cleaner features for diosgenin production or facilitate the transformation of other methods like enzymolysis, microbiological fermentation, or integrated methods from laboratory scale to industry scale.
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