间充质干细胞
利基
肺
细胞生物学
再生(生物学)
细胞
生物
解剖
医学
内科学
生态学
生物化学
作者
Dakota L. Jones,Michael P. Morley,Xinyuan Li,Yun Ying,Gan Zhao,Sarah E. Schaefer,L. Raposo Rodríguez,Fabian L. Cardenas‐Diaz,Shanru Li,Su Zhou,Ullas V. Chembazhi,Mijeong Kim,Chen Shen,Ana N. Nottingham,Susan M. Lin,Edward Cantu,Joshua M. Diamond,Maria C. Basil,Andrew E. Vaughan,Edward E. Morrisey
出处
期刊:Science
[American Association for the Advancement of Science]
日期:2024-12-12
卷期号:386 (6727)
被引量:14
标识
DOI:10.1126/science.ado5561
摘要
Severe lung injury causes airway basal stem cells to migrate and outcompete alveolar stem cells, resulting in dysplastic repair. We found that this "stem cell collision" generates an injury-induced tissue niche containing keratin 5
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