化学
色谱法
染发剂
液相色谱-质谱法
串联质谱法
甲醇
甲酸
电喷雾电离
质谱法
检出限
电喷雾
选择性反应监测
染色
有机化学
作者
Yu-Xiang Gu,Li‐Song Chen,Lei Nie
标识
DOI:10.1093/chromsci/bmad071
摘要
Abstract Eleven kinds of hair dyes were determined in hair-dyeing products by liquid chromatography–tandem mass spectrometry (MS). The samples were extracted with ultrasound in methanol for 20 min. After centrifugation, the supernatant was diluted with 10% methanol/90% water (v/v). Then, the solution was analyzed by Shim-pack Scepter C18–120 column (100 mm × 2.1 mm, 1.9 μm) plus electrospray ionization–MS/MS. Matrix-matched standard solutions were used to analyze the samples. The limits of detection were from 0.15 to 10 mg/kg, the limits of quantification were from 0.5 to 40 mg/kg and the recovery was from 79.4 to 109.2%. The protocol was selective and accurate and was satisfyingly applied to analyze hair dyes in different kinds of commercial products. 1-Hydroxyethyl-4,5-diaminopyrazole sulfate, hydroxyethyl-p-phenylenediamine sulfate, 2-methyl-5-hydroxyethylaminophenol, 5-amino-6-chloro-o-cresol, 3-nitro-p-hydroxyethylaminophenol and 2-amino-6-chloro-4-nitrophenol were detected in 10 samples with the concentrations between limits of detection and quantification to 9.27 × 104 mg/kg.
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