咖啡因
早晨
全国健康与营养检查调查
萧条(经济学)
医学
横断面研究
人口学
精神科
内科学
环境卫生
人口
病理
社会学
经济
宏观经济学
作者
Jiahui Yin,Di Yu,Fang Xu,Leiyong Zhao,Rixiang Gong,Jiguo Yang,Yuanxiang Liu
标识
DOI:10.1016/j.jad.2023.07.115
摘要
Recent research suggests that caffeine intake is associated with a reduced risk of depression. However, the relationship between caffeine intake during different periods of the day and depression is still unclear. This cross-sectional study analyzed noninstitutionalized adults from the National Health and Nutrition Examination Survey, with a weighted representation of approximately 218 million US adults. Covariate-adjusted sample-weighted regressions were used to examine associations between caffeine intake and depression in different periods. Caffeine intake during non-early morning periods (outside of 5:00–8:00 AM) is associated with a high prevalence of depression (unadjusted OR: 1.08, 95%CI: 1.05–1.11; adjusted OR: 1.03, 95 % CI: 1.00–1.06). Participants who consumed caffeine in the early morning (5:00–8:00 AM) had a lower prevalence of depression compared to participants who did not consume caffeine in the early morning (unadjusted OR: 0.75, 95%CI: 0.67–0.85; adjusted OR: 0.86, 95 % CI: 0.75–0.99). Cross-sectional study could not determine the temporal association; patients with depression in this study were not clinically diagnosed with Major Depressive Disorder. Among US adults, early morning caffeine consumers had a lower prevalence of depression than non-consumers; caffeine intake during non-early morning periods is associated with a high prevalence of depression. Our results may suggest the importance of caffeine intake time for depression.
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