Proceed With Caution: Eliminating Elective Nodal Irradiation With Immunotherapy for Head and Neck Cancer

Elective radiation of at-risk cervical nodal basins to address occult metastases has been a mainstay of definitive head and neck cancer therapy.1 More recently, however, deintensification approaches, with the goal of limiting radiation associated-toxicity, have led groups to evaluate reduced elective nodal treatment fields, with favorable results observed in phase II studies.2,3