Abstract Adsorption strategies have been used worldwide relentlessly for pollution abatement and remediation. Nanocomposites are the most promising nominees for high degree adsorption processes, and when collaborated with graphene oxide tend to emerge as very efficient candidates for adsorbing various pollutants present in water. The hybrid impact of graphene oxide and material nanocomposites have proved to make large contributions to the adsorption of heavy metals, hazardous organic chemicals (dyes, various VOCs, pesticides, fertilizers, drugs), and other particulate contaminants of water especially industrial wastewater. Graphene oxide contains a cluster of reactive oxygen functional groups anchored on the large surface of the nano-composites which develops remarkable stability and adsorption efficacy in aqueous medium and makes them reusable for multiple number of adsorption-desorption cycles. The current chapter highlights all such adsorption phenomenon for water to decontaminate it and make it salubrious.