受体
细胞生物学
酶联受体
信号转导
5-HT5A受体
免疫受体
白细胞介素-21受体
功能(生物学)
生物
效应器
细胞表面受体
细胞外
G蛋白偶联受体
化学
生物物理学
生物化学
出处
期刊:Molecular Pharmacology
[American Society for Pharmacology & Experimental Therapeutics]
日期:2017-08-01
卷期号:92 (3): 185-187
被引量:1
标识
DOI:10.1124/mol.117.109587
摘要
A receptor is a protein molecule that receives chemical signals from outside a cell, which enables the cell to respond to the signal molecule. Receptors mediate numerous important physiologic effects upon binding extracellular agonists. However, sustained activation of the receptor may lead to pathologic effects. Cells can regulate the number and function of receptors to alter their sensitivity to different molecules by a feedback mechanism, such as change in the receptor conformation, uncoupling of the receptor effector molecules, receptor sequestration, etc. In this special issue, some Chinese scientists were invited to contribute impactful discoveries and insightful reviews in the field of molecular pharmacology, especially receptor and receptor regulation.
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