Multiple‐Organocatalyst‐Promoted Cascade Reaction: A Fast and Efficient Entry into Fully Substituted Piperidines

Multiple reactions in a single pot: The development of a catalytic asymmetric approach to fully substituted piperidines, which previously remained elusive, is achieved by the use of a multi-catalyst-promoted cascade reaction (see scheme). The one-pot reaction cascade is easy to perform, highly stereoselective and broad in scope, and the reaction products are high-value intermediates for multiple synthetic transformations.