Nucleophilic Substitution Reactions. IV. Further Details
作者
Steven M. Bachrach
出处
期刊:Oxford University Press eBooks [Oxford University Press] 日期:2023-04-20卷期号:: 76-87
标识
DOI:10.1093/oso/9780197640371.003.0009
摘要
Abstract A few details of nucleophilic substitution are presented. Solvent polarity and ability to participate in hydrogen bonding allow for the selection between the SN1 and SN2 reactions. Isotopes enable close examination of nucleophilic reactions. The endocyclic restriction test implicates a backside attack in the SN2 reaction.