检出限
碘化物
化学
生物相容性
碘
基质(水族馆)
生物传感器
核化学
离子
无机化学
组合化学
色谱法
生物化学
有机化学
海洋学
地质学
作者
Xin Zhang,Ziting Lin,Yuanyuan Cai,Xuan Li,Lingxi Niu,Aihua Liu
标识
DOI:10.1016/j.snb.2023.134127
摘要
Nanozymes continue to attract great interest due to their high enzyme activities, good biocompatibility, chemical stability and adjustable activity, which have been widely used in biosensing, disease therapy and antibacterial treatment. Herein we report porous MoS2 particles to have both excellent bromoperoxidase-like and iodoperoxidase-like activity. The MoS2 particles exhibited the highest Vmax value of 83 µM/s (H2O2 as substrate), remarkably superior to haloperoxidase and other haloperoxidase-like reported so far. The underlying mechanism of the iodoperoxidase mimics is oxygen vacancies. The iodoperoxidase-like can catalyze the oxidization of iodide ions (I−) by H2O2 to iodic acid (HIO3), which further enables to readily oxidize colorless 3,3’,5,5’-tetramethylbenzidine to green ox-TMB. Significantly, among the halogen anions (Cl−, Br− and I−), only I− was found to cause this oxidation reaction to occur. Thereafter, a fast, selective and cost-effective colorimetric detection of I− ion was developed with the linear range of 0.5–70 μM and detection limit of 292 nM (3σ/S). Further, the as-developed assay was applicable to detect seawater and human urines samples with satisfactory recoveries and accuracy. Thus the colorimetric assay based on MoS2 particles with haloperoxidase-like activity show great promise for I− sensing in environmental analysis and biochemical analysis.
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